Top CAR-T Manufacturing Companies to Watch in 2024

Are you on the hunt for the perfect car manufacturing partner but feeling overwhelmed by choices? With so many options out there, finding the right supplier can feel like searching for a needle in a haystack. Choosing a top-tier factory not only ensures quality and reliability but can also save you time and money in the long run. Imagine driving your project forward with a trusted partner who understands your vision and delivers exceptional results.

In this article, we’ll compare the leading car manufacturing companies and their factories, helping you make an informed decision. Ready to unlock the secrets of the best in the business? Let’s dive in!

55 CAR-T Companies Worldwide – Biotech Careers

List of CAR T-Cell Companies Worldwide 2024 – OneDayMD

Product Details:
CAR-T therapies developed by various companies, including proprietary technologies for enhancing safety, versatility, and efficacy in treating cancers.

Technical Parameters:
– Switchable CAR-T platform by Calibr
– Affinity-enhanced T-cell therapies by Adaptimmune
– Non-viral Sleeping Beauty platform by Alaunos
– Chimeric endocrine receptor T-cell (CER-T) technology by Anixa

Application Scenarios:
– Treatment of solid tumors and hematological malignancies
– Triple negative breast cancer (TNBC) immunotherapy
– Rapid manufacturing of genetically modified CAR+ T cells
– Cancer cell metabolism targeting therapies

Pros:
– Enhanced safety and efficacy through innovative platforms
– Utilization of the body’s immune system to fight cancer
– Rapid manufacturing capabilities for CAR-T cells
– Broad range of cancer types targeted by various therapies

Top 5 CAR T Companies to Look for in 2024 – Roots Analysis

Eight CAR-T cell therapy companies you should know about – Labiotech.eu

Product Details:
Allogene Therapeutics develops allogeneic CAR-T cell therapy products, including cema-cel, an anti-CD19 CAR T therapy in phase 2 trials for large B-cell lymphoma and phase 1 trials for chronic lymphocytic leukemia. Anixa Biosciences focuses on CAR-T targeting CD19 and a new CER T therapy for ovarian cancer. Autolus Therapeutics offers obe-cel, targeting CD19 for relapsed/refractory adult B-cell acute lymphoblastic leukemia. BioNTech’s BNT211 targets Claudin-6 with an autologous CAR-T cell therapy and a CARVac RNA vaccine.

Technical Parameters:
– cema-cel: anti-CD19 CAR T therapy
– obe-cel: designed to bind-off quickly to minimize excessive activation
– BNT211: combines CAR-T cell therapy with mRNA technology
– CER T therapy: targets follicle stimulating hormone receptor (FSHR)

Application Scenarios:
– Treatment of large B-cell lymphoma
– Chronic lymphocytic leukemia
– Ovarian cancer
– Advanced solid tumors

Pros:
– Allogeneic therapies can be more readily available than autologous therapies.
– Target-specific approaches minimize damage to healthy cells.
– High overall response rates observed in clinical trials.
– Innovative combination therapies using mRNA technology enhance CAR-T

Cons:
– Some trials have been halted to refocus on different patient populations.
– Potential side effects from engineered T cells.
– Limited data on long-term efficacy and safety.
– Complex manufacturing processes for CAR-T therapies.

Top 30 CAR-T startups (May 2025) – Medical Startups

Product Details:
CAR T-cell therapy – a form of immunotherapy that uses specially altered T cells to fight cancer.

Technical Parameters:
– Utilizes advanced cell programming CAR-T and manufacturing technologies
– Employs genome engineering capabilities
– Develops adoptive immunotherapies for cancer

Application Scenarios:
– Treatment of haematological malignancies
– Treatment of solid tumors
– Targeting B cell-mediated autoimmune diseases

Pros:
– Innovative approach to cancer treatment
– Potential for targeted lifesaving therapeutics
– Focus on developing safer and more efficacious treatments

Cons:
– Potential serious side effects associated with CAR-T therapy
– Complex manufacturing processes
– High cost of development and treatment

Top Companies in CAR T-cell Therapy (2024) – Aesthetics Advisor

Product Details:
AbbVie is co-developing CAR-T therapies aimed at solid tumors and other cancers with Calibr, utilizing a switchable CAR-T platform. Adaptimmune is developing SPEAR T-cells targeting multiple myeloma and non-small cell lung cancer. Agios is developing a BCMA CAR-T therapy for relapsed/refractory multiple myeloma. Alaunos is advancing CAR-T therapies using a controlled IL-12 platform and a Sleeping Beauty platform for solid tumors. Allife is developing a CD19 CAR-T therapy for relapsed/refractory B-cell acute lymphoblastic leukemia.

Technical Parameters:
– Switchable CAR-T platform by Calibr
– SPEAR T-cell technology
– Controlled IL-12 platform
– Sleeping Beauty platform

Application Scenarios:
– Treatment of hematologic malignancies
– Treatment of solid tumors
– Targeting specific tumor antigens
– Rapid manufacturing of genetically modified CAR+ T cells

Pros:
– Enhanced safety, versatility, and efficacy through switchable CAR-T technology
– Robust pipeline with multiple INDs open for Adaptimmune
– Potential for rapid manufacturing of CAR+ T cells
– Targeted therapies for specific cancer types

Cons:
– No specific CAR-T technology details provided for some companies
– Limited information on the success rates of therapies
– Potential challenges in the commercialization of new CAR-T products
– Development timelines may vary significantly

CAR-T Manufacturing Services | Charles River

Product Details:
Full CDMO capabilities for CAR-T cell manufacturing, including analytical and process development expertise, in-house testing capabilities, and customizable manufacturing solutions.

Technical Parameters:
– Utilization of lentivirus or non-viral methods such as electroporation for CAR
– Implementation of automated and closed systems for scalable manufacturing
– Comprehensive quality control measures to assess genetic integrity throughout

Application Scenarios:
– Development of personalized therapies using autologous cells.
– Creation of therapies at scale using allogeneic donor-based starting materials.
– Support for early-phase development with flexible manufacturing options.

Pros:
– Unparalleled flexibility in manufacturing processes (closed, automated, or
– Expertise in both autologous and allogeneic CAR-T manufacturing solutions.
– Strict adherence to regulatory compliance and quality control standards.

Global CAR T-Cell Therapy Company List – Mordor Intelligence

The Automobile Industry in Buffalo

CAR-T Therapy Manufacturing – Sartorius

Product Details:
Sartorius offers a comprehensive range of products and services for CAR-T cell therapy manufacturing, including cell culture media, bioreactors, and analytical solutions.

Technical Parameters:
– Cell culture media optimized for T cell expansion
– Single-use bioreactors for scalable production
– Automated cell processing systems
– Analytical tools for quality control

Application Scenarios:
– Manufacturing CAR-T cells for clinical applications
– Research and development in cell therapy
– Quality assurance in cell processing
– Scale-up processes for commercial production

Pros:
– High scalability of production systems
– Optimized media for enhanced cell growth
– Integrated solutions for streamlined workflows
– Robust analytical tools for quality assurance

Cons:
– Potentially high costs associated with advanced technologies
– Complexity in system integration
– Need for specialized training to operate advanced equipment
– Regulatory challenges in product approval

Comparison Table

Company Product Details Pros Cons Website
55 CAR-T Companies Worldwide – Biotech Careers www.biotech-careers.org
List of CAR T-Cell Companies Worldwide 2024 – OneDayMD CAR-T therapies developed by various companies, including proprietary Enhanced safety and efficacy through innovative platforms Utilization of the www.onedaymd.com
Top 5 CAR T Companies to Look for in 2024 – Roots Analysis www.rootsanalysis.com
Eight CAR-T cell therapy companies you should know about – Labiotech.eu Allogene Therapeutics develops allogeneic CAR-T cell therapy products, Allogeneic therapies can be more readily available than autologous therapies Some trials have been halted to refocus on different patient populations www.labiotech.eu
Top 30 CAR-T startups (May 2025) – Medical Startups CAR T-cell therapy – a form of immunotherapy that uses specially altered T Innovative approach to cancer treatment Potential for targeted lifesaving Potential serious side effects associated with CAR-T therapy Complex www.medicalstartups.org
Top Companies in CAR T-cell Therapy (2024) – Aesthetics Advisor AbbVie is co-developing CAR-T therapies aimed at solid tumors and other cancers Enhanced safety, versatility, and efficacy through switchable CAR-T No specific CAR-T technology details provided for some companies Limited stemcell.aestheticsadvisor.com
CAR-T Manufacturing Services Charles River Full CDMO capabilities for CAR-T cell manufacturing, including analytical and Unparalleled flexibility in manufacturing processes (closed, automated, or
Global CAR T-Cell Therapy Company List – Mordor Intelligence www.mordorintelligence.com
The Automobile Industry in Buffalo buffaloah.com
CAR-T Therapy Manufacturing – Sartorius Sartorius offers a comprehensive range of products and services for CAR-T cell High scalability of production systems Optimized media for enhanced cell Potentially high costs associated with advanced technologies Complexity in www.sartorius.com

Top CAR-T Manufacturing Companies to Watch in 2024

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